Table 2 Potential urinary protein biomarkers for the cigarette smoke-induced COPD
From: Proteome analysis of urinary biomarkers in a cigarette smoke-induced COPD rat model
Accession | Protein names | Human orthologs | Trend | Biomarkes | COPD-related |
|---|---|---|---|---|---|
Q9WUW9 | Sulfotransferase 1C2A | O00338 | ↑ | ||
P29598 | Urokinase-type plasminogen activator | P00749 | ↑ | Yes | |
Q01177 | Plasminogen | P00747 | ↑ | Hepatocellular carcinoma [32], Acute-on-chronic liver failure [33] | Yes |
P04937 | Fibronectin | P02751 | ↑ | Yes | |
Q920A6 | Retinoid-inducible serine carboxypeptidase | Q9HB40 | ↑ | ||
P08592 | Amyloid-beta precursor protein | P05067 | ↓ | ||
B5DFC9 | Nidogen-2 | Q14112 | ↓ | Ovarian cancer [35] | |
P31044 | Phosphatidylethanolamine-binding protein 1 | P30086 | ↑ | ||
Q9JI85 | Nucleobindin-2 | P80303 | ↑ | Breast cancer [36] | |
P19804 | Nucleoside diphosphate kinase B | P22392 | ↑ | ||
Q6AYR9 | Tetraspanin-1 | O60635 | ↑ | Colon cancer [37], Acute rejection in kidney transplantation [38] | |
Q09030 | Trefoil factor 2 | Q03403 | ↓ | Pancreatic cancer [39], Precancerous lesion [40], COPD [26, 27] | Yes |
Q9JHY1 | Junctional adhesion molecule A | Q9Y624 | ↓ |