Table 1 Baseline characteristics of the PPFE and no-PPFE groups of patients with RA-ILD
From: Pleuroparenchymal fibroelastosis in rheumatoid arthritis-associated interstitial lung disease
Variables | Total | PPFE | No PPFE | p-value |
|---|---|---|---|---|
Number of patients | 477 | 31 | 446 | Â |
Age | 63.4 ± 9.8 | 65.7 ± 10.6 | 63.2 ± 9.7 | 0.165 |
Men | 191 (40.0) | 12 (38.7) | 179 (40.1) |  > 0.999 |
Ever-smoker | 183 (38.4) | 10 (32.3) | 173 (38.8) | 0.568 |
BMI | 23.6 ± 3.1 | 21.4 ± 2.3 | 23.7 ± 3.1 |  < 0.001 |
ESR | 40.0 [23.0;67.0] | 43.0 [26.5;75.0] | 40.0 [22.0;67.0] | 0.517 |
CRP | 1.0 [0.2;4.7] | 3.0 [0.6;10.7] | 0.9 [0.2;4.4] | 0.017 |
RF | 391 (82.0) | 28 (93.3) | 363 (83.3) | 0.200 |
RF titre | 120.0 [43.7;363.0] | 120.0 [39.1;439.8] | 120.0 [44.3;351.5] | 0.875 |
Anti-CCP | 377 (79.0) | 29 (96.7) | 348 (84.5) | 0.103 |
Anti-CCP titre | 200.0 [41.8;340.0] | 200.0 [60.8;559.9] | 200.0 [40.5;340.0] | 0.175 |
Pulmonary function | Â | Â | Â | Â |
 FVC (%pred.) | 78.0 ± 18.3 | 70.2 ± 20.0 | 78.5 ± 18.1 | 0.016 |
 FEV1 (%pred.) | 84.2 ± 21.1 | 79.6 ± 23.5 | 84.5 ± 20.9 | 0.220 |
 FEV1/FVC | 80.3 ± 8.8 | 82.4 ± 8.5 | 80.1 ± 8.8 | 0.171 |
 DLCO (%pred.) | 66.6 ± 20.0 | 62.1 ± 22.5 | 66.9 ± 19.8 | 0.204 |
 TLCa (%pred.) | 76.7 ± 16.1 | 72.8 ± 19.9 | 76.9 ± 16.0 | 0.393 |
 RVa (%pred.) | 66.1 ± 20.1 | 69.6 ± 25.5 | 65.9 ± 20.0 | 0.548 |
 RV/TLCa | 0.8 [0.7;1.0] | 0.9 [0.8;1.3] | 0.8 [0.7;0.9] | 0.084 |
UIP-like pattern on HRCT | 260 (54.5) | 23 (74.2) | 237 (53.1) | 0.023 |
Treatment | Â | Â | Â | 0.556 |
 None | 318 (66.7) | 19 (61.3) | 299 (67.0) |  |
 Corticosteroid ± IMb | 159 (33.3) | 12 (38.7) | 147 (33.0) |  |