Table 4 Association between degree of lung function impairment (FEV1% predicted) and all-cause mortality by country
From: Impaired lung function and mortality in Eastern Europe: results from multi-centre cohort study
Type of groups | No. of persons | No. of deaths | Person-years of follow-up | Deaths per 100 person-years (95% CI) | Model 1 adjusted HR† (95% CI) | Model 2 adjusted HR‡ (95% CI) |
|---|---|---|---|---|---|---|
Czech Republic | ||||||
FEV1% predicted impairment groups* | ||||||
Normal | 5283 | 1081 | 84,319 | 1.28 (1.21–1.36) | 1.00 | 1.00 |
Mild | 831 | 268 | 12,636 | 2.12 (1.88–2.39) | 1.54 (1.34–1.76) | 1.31 (1.13–1.52) |
Moderate | 366 | 140 | 5347 | 2.62 (2.22–3.09) | 1.71 (1.43–2.05) | 1.25 (1.02–1.53) |
Moderate-severe | 135 | 56 | 1915 | 2.92 (2.25–3.80) | 2.01 (1.52–2.67) | 1.49 (1.10–2.01) |
Severe | 110 | 49 | 1469 | 3.33 (2.52–4.41) | 2.36 (1.73–3.21) | 1.85 (1.34–2.53) |
Very severe | 29 | 18 | 357 | 5.04 (3.17–8.00) | 3.53 (2.18–5.72) | 2.99 (1.76–5.09) |
Russia | ||||||
FEV1% predicted impairment groups* | ||||||
Normal | 5621 | 1114 | 70,294 | 1.58 (1.49–1.68) | 1.00 | 1.00 |
Mild | 595 | 180 | 7060 | 2.55 (2.20–2.95) | 1.39 (1.19–1.63) | 1.11 (0.95–1.31) |
Moderate | 262 | 106 | 2810 | 3.77 (3.12–4.56) | 2.15 (1.75–2.64) | 1.68 (1.37–2.06) |
Moderate-severe | 163 | 75 | 1699 | 4.42 (3.52–5.54) | 2.31 (1.79–2.99) | 1.69 (1.33–2.15) |
Severe | 116 | 56 | 1239 | 4.52 (3.48–5.87) | 2.11 (1.59–2.80) | 1.61 (1.22–2.11) |
Very severe | 46 | 31 | 390 | 7.96 (5.60–11.31) | 3.63 (2.36–5.58) | 2.98 (2.07–4.30) |
Poland | ||||||
FEV1% predicted impairment groups* | ||||||
Normal | 3650 | 533 | 46,585 | 1.14 (1.05–1.25) | 1.00 | 1.00 |
Mild | 504 | 111 | 6188 | 1.79 (1.49–2.16) | 1.53 (1.25–1.87) | 1.20 (0.96–1.50) |
Moderate | 234 | 66 | 2786 | 2.37 (1.86–3.01) | 1.98 (1.53–2.56) | 1.63 (1.24–2.13) |
Moderate-severe | 97 | 45 | 1026 | 4.39 (3.27–5.87) | 3.38 (2.46–4.64) | 2.40 (1.73–3.33) |
Severe | 59 | 29 | 597 | 4.85 (3.37–6.99) | 3.08 (2.06–4.61) | 2.12 (1.39–3.24) |
Very severe | 14 | 9 | 120 | 7.48 (3.89–14.37) | 6.95 (3.49–13.84) | 4.28 (2.14–8.56) |
Lithuania | ||||||
FEV1% predicted impairment groups* | ||||||
Normal | 5952 | 904 | 66,422 | 1.36 (1.28–1.45) | 1.00 | 1.00 |
Mild | 522 | 141 | 5467 | 2.58 (2.19–3.04) | 1.87 (1.56–2.24) | 1.50 (1.25–1.81) |
Moderate | 206 | 82 | 1935 | 4.24 (3.41–5.26) | 2.84 (2.24–3.60) | 2.04 (1.57–2.65) |
Moderate-severe | 92 | 43 | 825 | 5.21 (3.86–7.02) | 2.83 (2.00–3.99) | 2.18 (1.59–2.99) |
Severe | 57 | 29 | 508 | 5.71 (3.96–8.21) | 3.00 (2.02–4.46) | 2.01 (1.37–2.94) |
Very severe | 15 | 11 | 94 | 11.71 (6.48–21.14) | 5.79 (2.54–13.19) | 4.07 (2.21–7.50) |