The impact of IgG subclass deficiency on the risk of mortality in hospitalized patients with COPD

Respiratory Research

Table 2 Unadjusted and adjusted HRs related to 1-year mortality according to IgG subclass deficiency

Type of IgG deficiency	Number at risk	1-year mortality	Unadjusted model		Adjusted model^*
Type of IgG deficiency	Number at risk	1-year mortality	Unadjusted HR (95% CI)	p value	Adjusted HR (95% CI)	p value
IgG1 deficiency	9	55.6% (5/9)	3.80 (1.54– 9.41)	0.004	3.92 (1.55–9.87)	0.004
IgG2 deficiency^†	59	27.1% (16/59)	1.36 (0.79–2.33)	0.265	NA^†	NA^†
IgG3 deficiency	21	23.8% (5/21)	1.29 (0.52–3.20)	0.577	1.27 (0.51–3.15)	0.612
IgG4 deficiency	55	30.9% (17/55)	1.65 (0.97–2.79)	0.063	1.74 (1.02–2.98)	0.043

Data are presented as number, percentage, or ratios (95% CIs)
HR hazard ratio, IgG immunoglobulin G, CI confidence interval
*Adjusted for age, sex, ethnicity (white vs. other ethnicities), smoking status (current vs. non-current), asthma status, and cardiac comorbidity status
^†The proportional hazards assumption was not met

ISSN: 1465-993X