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Table 1 Baseline characteristics of study participants

From: The impact of IgG subclass deficiency on the risk of mortality in hospitalized patients with COPD

 

Total (N = 489)

Age, years

67.3 ± 11.6

Male

309 (63.2)

Ethnicity, white

391 (81.0)

Smoking status

 Current smoker

287 (58.7)

 Ex-smoker

173 (35.4)

 Never smoker

29 (5.9)

 Asthma

119 (24.4)

 Cardiac comorbidities*

182 (37.3)

Lung function

 Post-bronchodilator FVC, L

2.8 ± 1.1

 Post-bronchodilator FVC, %predicted

77.6 ± 23.1

 Post-bronchodilator FEV1, L

1.5 ± 0.8

 Post-bronchodilator FEV1, %predicted

53.7 ± 23.8

 Post-bronchodilator FEV1/FVC

45.2 ± 24.8

IgG subclass deficiency

 IgG1 deficiency

9 (1.8)

 IgG2 deficiency

59 (12.1)

 IgG3 deficiency

21 (4.3)

 IgG4 deficiency

55 (11.3)

 1-year mortality

101 (20.7)

  1. Data are presented as numbers (%) or mean ± SD
  2. FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, IgG immunoglobulin G
  3. *Cardiac comorbidities included a history of heart failure, myocardial infarction, stable coronary disease, or coronary artery bypass graft surgery