Fig. 4

Changes in airway mucus production and serum IgE. A Representative images of PAS-stained mouse lung sections taken at ×100 magnification, scale bar = 250 μm. Dark purple staining in the airway epithelium indicates positive PAS staining. B Mean peribronchial mucus score of PAS-stained lung sections, n = 12–18 mice per group, 9 airways per mouse. C Changes in whole lung Muc5ac mRNA expression, n = 5–8 mice per group. D Changes is total serum IgE levels as measured by ELISA, n = 10–16 mice per group. *p < 0.05, **p < 0.01, ****p < 0.0001 vs. corresponding PBS treatment by two-way ANOVA with Šidák correction