Fig. 4From: Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscleDifferential gene expression and pathway analysis in response to TNFα and fluticasone propionate (FP). Volcano plots for differentially expressed genes in A TNFα vs. control, B FP + TNFα vs. control, and C FP + TNFα vs. TNFα are displayed. Volcano plots are represented by plotting -log10 (adjusted p value) and log2 fold change. The total number of significantly up-regulated and down-regulated genes are stated. Top 10 D KEGG and Reactome terms and E enriched transcription factor motifs. Enrichment is represented by plotting -log10 (adjusted p value)Back to article page