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Fig. 1 | Respiratory Research

Fig. 1

From: NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial–mesenchymal transition

Fig. 1

NecroX-5 ameliorated pulmonary fibrosis in BLM-treated mice. A Masson’s trichrome staining. B Lung fibrosis score. C Lung tissue levels of hydroxyproline at Day 14. D Lung tissue levels of COL-1. E cytokeratin-8 mRNA expression in lung tissue. F E-cadherin mRNA expression in lung tissue. G α-SMA mRNA expression in lung tissue. H vimentin mRNA expression in lung tissue. I The expression of epithelial markers (cytokeratin-8, E-cadherin) and mesenchymal markers (α-SMA, vimentin) in lung tissue was confirmed by immunostaining. *P < 0.05, vs. controls; &P < 0.05 vs. BLM

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Respiratory Research

ISSN: 1465-993X

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