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Table 2 Reason for changing or remaining on therapy (safety set)

From: Impact of switching from triple therapy to dual bronchodilation in COPD: the DACCORD ‘real world’ study

LABA/LAMA FDC (N = 340)

Triple therapy (N = 784)

Reason to change therapy*, n (%)

 

Reason to remain on therapy, n (%)

 

Physician prefers other inhaler

14 (4.1)

Physician prefers current inhaler(s)

61 (7.8)

Physician prefers FDC

56 (16.5)

Established control of COPD symptoms

275 (35.1)

Exacerbation(s) with current COPD medication

1 (0.3)

Good tolerability

101 (12.9)

Side effect(s) with current COPD medication

5 (1.5)

Patient prefers current inhaler(s)

34 (4.3)

Patient still symptomatic with current COPD medication

25 (7.4)

Patient's wish

37 (4.7)

Patient prefers FDC

31 (9.1)

Considered necessary for exacerbation prevention

255 (32.5)

Patient prefers other inhaler

10 (2.9)

Other main reason

12 (1.5)

Patient's wish

87 (25.6)

Missing values

9 (1.1)

Other main reason

96 (28.2)

  

Missing values

15 (4.4)

  
  1. *Only for patients in the LABA/LAMA FDC treatment group. Only for patients in the triple therapy treatment group. LABA long-acting β2-agonist, LAMA long-acting muscarinic antagonist, FDC fixed-dose combination, COPD chronic obstructive pulmonary disease