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Table 2 Comparison of sputum cytokines within the three clusters

From: Clinical and cytokine patterns of uncontrolled asthma with and without comorbid chronic rhinosinusitis: a cross-sectional study

Parameters Cluster 1 (n = 5) Cluster 2 (n = 9) Cluster 3 (n = 9) p value
Male, n (%) 1 (20.0) 1 (11.1) 4 (44.4) 0.257
Age (years) 55.0 (52.5, 73.5) 63.0 (49.5, 74.0) 62.0 (45.0, 65.5) 0.916
IL-5 (μg/ml) 0 (0,1.16) 0 (0, 0.98) 7.23 (3.39, 7.85) < 0.001*
IL-4 (μg/ml) 24.5 (21.2, 49.6) 32.9 (19.3, 39.9) 78.3 (51.5, 266.9) 0.007*
IL-13 (μg/ml) 0 (0, 410) 249 (0, 315) 825 (463, 1924) 0.002*
IL-25 (μg/ml) 0 (0, 399) 133 (0, 186) 317 (138, 2946) 0.058
IL-33 (μg/ml) 0 (0, 2.92) 0 (0, 0) 10.00 (6.31, 36.49) < 0.001*
IFN-γ (μg/ml) 0 (0, 17.1) 0 (0, 21.2) 42.4 (20.0, 150.0) 0.013*
IL-10 (μg/ml) 8.81 (0, 10.60) 9.88 (0, 12.90) 12.00 (4.59, 46.10) 0.210
IL-17 (μg/ml) 0 (0, 9.26) 5.66 (0.00, 6.57) 17.60 (7.31, 83.90) 0.012*
TNF-α (μg/ml) 0 (0, 7.64) 3.01 (0.00, 5.44) 19.60 (8.56, 73.00) 0.002*
  1. IL interleukin, IFN interferon, TNF tumor necrosis factor. *statistical significance. values are presented as medians (25–75% interquartile range)