|
Parameters
|
Cluster 1 (n = 5)
|
Cluster 2 (n = 9)
|
Cluster 3 (n = 9)
|
p value
|
|---|
|
Male, n (%)
|
1 (20.0)
|
1 (11.1)
|
4 (44.4)
|
0.257
|
|
Age (years)‡
|
55.0 (52.5, 73.5)
|
63.0 (49.5, 74.0)
|
62.0 (45.0, 65.5)
|
0.916
|
|
IL-5 (μg/ml)‡
|
0 (0,1.16)
|
0 (0, 0.98)
|
7.23 (3.39, 7.85)
|
< 0.001*
|
|
IL-4 (μg/ml)‡
|
24.5 (21.2, 49.6)
|
32.9 (19.3, 39.9)
|
78.3 (51.5, 266.9)
|
0.007*
|
|
IL-13 (μg/ml)‡
|
0 (0, 410)
|
249 (0, 315)
|
825 (463, 1924)
|
0.002*
|
|
IL-25 (μg/ml)‡
|
0 (0, 399)
|
133 (0, 186)
|
317 (138, 2946)
|
0.058
|
|
IL-33 (μg/ml)‡
|
0 (0, 2.92)
|
0 (0, 0)
|
10.00 (6.31, 36.49)
|
< 0.001*
|
|
IFN-γ (μg/ml)‡
|
0 (0, 17.1)
|
0 (0, 21.2)
|
42.4 (20.0, 150.0)
|
0.013*
|
|
IL-10 (μg/ml)‡
|
8.81 (0, 10.60)
|
9.88 (0, 12.90)
|
12.00 (4.59, 46.10)
|
0.210
|
|
IL-17 (μg/ml)‡
|
0 (0, 9.26)
|
5.66 (0.00, 6.57)
|
17.60 (7.31, 83.90)
|
0.012*
|
|
TNF-α (μg/ml)‡
|
0 (0, 7.64)
|
3.01 (0.00, 5.44)
|
19.60 (8.56, 73.00)
|
0.002*
|
- IL interleukin, IFN interferon, TNF tumor necrosis factor. *statistical significance. ‡values are presented as medians (25–75% interquartile range)
