Table 7 Clinical baseline characteristics, Changes of hemodynamics and NT-proBNP in the initial BPA session
| Â | First BPA sessions | Unilateral BPA | Bilateral BPA | *p value |
|---|---|---|---|---|
Clinical baseline characteristics (N) | 92 | 54 | 38 | Â |
Age (years) | 59 ± 12 | 60 ± 13 | 56 ± 11 | 0.10 |
Female (%) | 63 (68%) | 40 (74%) | 23 (61%) | 0.17 |
Heart rate | 80.5 ± 13.2 | 79.0 ± 13.3 | 82.7 ± 12.8 | 0.20 |
Mean PAP (mmHg) | 43.0 ± 13.6 | 41.9 ± 13.8 | 44.5 ± 13.3 | 0.37 |
PVR (Wood Unit) | 8.9 (4.9, 15.1) | 8.3 (5.1, 15.9) | 9.9 (4.6, 14.1) | 0.92 |
Cardiac output (L/min) | 3.6 (2.7, 5.0) | 3.4 (2.6, 5.5) | 3.8 (3.3, 5.0) | 0.18 |
Cardiac index (L/min/m2) | 2.2 (1.7, 3.2) | 2.1 (1.7, 3.2) | 2.5 (2.1, 3.2) | 0.22 |
NT-proBNP (pg/ml) | 541.1 (120.0, 1823.8) | 321.1 (120.0, 1816.0) | 950.3 (110.4, 2092.3) | 0.34 |
WHO functional class (I–II/III–IV) | 56.5%/43.5% | 57.4%/42.6% | 55.3%/44.7% | 0.84 |
Interval between BPA (days) | 67 (35, 107) | 64 (30, 94) | 95 (63, 185) | 0.02 |
Changes of hemodynamics (N) | 62 | 39 | 23 | Â |
Heart rate | − 5.3 ± 11.8 | − 3.7 ± 10.9 | − 7.9 ± 12.9 | 0.18 |
Mean RAP (mmHg) | 0.0 (− 4.0, 3.0) | 0.0 (− 4.0, 3.3) | − 1.0 (− 3.5, 2.0) | 0.54 |
Systolic PAP (mmHg) | − 8.9 ± 14.7 | − 7.3 ± 13.3 | − 11.6 ± 16.8 | 0.28 |
Diastolic PAP (mmHg) | − 2.9 ± 6.9 | − 2.4 ± 7.4 | − 3.8 ± 5.9 | 0.45 |
Mean PAP (mmHg) | − 5.1 ± 8.2 | − 4.1 ± 7.4 | − 6.8 ± 9.3 | 0.22 |
Cardiac output (L/min) | 0.0 (− 0.6, 0.9) | 0.0 (− 0.8, 0.9) | 0.0 (− 0.5, 0.9) | 0.62 |
Cardiac index (L/min/m2) | 0.0 (− 0.4, 0.5) | 0.0 (− 0.5, 0.5) | 0.1 (− 0.2, 0.5) | 0.41 |
PVR (Wood Unit) | − 1.8 (− 4.5, 0.8) | − 1.8 (− 4.2, 0.7) | − 1.5 (− 5.8, 0.9) | 0.99 |
PASO2 (%) | 1.1 ± 7.5 | 0.9 ± 6.6 | 1.5 ± 8.9 | 0.77 |
MVSO2 (%) | 0.1 ± 4.4 | 0.4 ± 4.2 | − 0.2 ± 4.9 | 0.62 |
Changes of NT-proBNP (pg/ml) | − 131.3 (− 937.8, 2.5) | − 109.3 (− 725.4, − 2.4) | − 488.0 (− 1359.2, 19.5) | 0.53 |