Skip to main content

Table 1 Pleiotropy and heterogeneity test of insomnia on allergic disease, asthma and its phenotypes

From: Exploring genetic association of insomnia with allergic disease and asthma: a bidirectional Mendelian randomization study

Outcomes MR-Egger Test Cochrane Q Test MR-PRESSO Global Test
MR-Egger IVW
Intercept SE P-value Q Q_df I2 P-value Q Q_df I2 P-value RSSobs P-value
Allergic disease 0.002 0.002 0.360 218.5 194 0.112 0.110 219.0 195 0.110 0.110 221.750 0.104
Asthma 0.004 0.003 0.135 130.7 111 0.151 0.098 133.3 112 0.160 0.083 136.229 0.071
Moderate-severe asthma − 0.018 0.009 0.038 182.6 174 0.047 0.312 187.2 175 0.065 0.250 189.379 0.250
Adult-onset asthma 0.007 0.004 0.062 140.9 118 0.163 0.074 145.1 119 0.180 0.052 148.374 0.053
Childhood asthma 0.002 0.006 0.747 129.9 114 0.123 0.146 130.0 115 0.116 0.160 132.260 0.161
  1. SE standard error, df degree of freedom