Allergens | 0–1 years (n = 2373) | p | > 1–3 years (n = 5517) | p | > 3–6 years (n = 17,689) | p | > 6–12 years (n = 12,893) | p | > 12-18y (n = 1454) | p | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Male (n = 1448) | Female (n = 925) | Male (n = 3216) | Female (n = 2301) | Male (n = 10,461) | Female (n = 7228) | Male (n = 8048) | Female (n = 4845) | Male (n = 884) | Female (n = 570) | ||||||
Dust mite | 18 (1.2) | 16 (1.7) | 0.331 | 163 (5.1) | 79 (3.4) | 0.003 | 1723 (16.5) | 1035 (14.3) | < 0.001# | 2183 (27.1) | 1138 (23.5) | < 0.001# | 304 (34.4) | 157 (27.5) | 0.006 |
House mite | 39 (2.7) | 16 (1.7) | 0.128 | 431 (13.4) | 248 (10.8) | 0.003 | 3922 (37.5) | 2398 (33.2) | < 0.001# | 4024 (50.0) | 2151 (44.4) | < 0.001# | 510 (57.7) | 268 (47.0) | < 0.001# |
Cat epithelium | 130 (9.0) | 70 (7.6) | 0.228 | 338 (10.5) | 198 (8.6) | 0.018 | 881 (8.4) | 488 (6.8) | < 0.001# | 753 (9.4) | 396 (8.2) | 0.022 | 108 (12.2) | 57 (10.0) | 0.19 |
Dog epithelium | 43 (3.0) | 28 (3.0) | 0.94 | 194 (6.0) | 109 (4.7) | 0.037 | 747 (7.1) | 397 (5.5) | < 0.001# | 543 (6.7) | 269 (5.6) | 0.007 | 69 (7.8) | 33 (5.8) | 0.14 |
Cockroach | 13 (0.9) | 12 (1.3) | 0.35 | 48 (1.5) | 29 (1.3) | 0.47 | 227 (2.2) | 136 (1.9) | 0.18 | 186 (2.3) | 93 (1.9) | 0.14 | 15 (1.7) | 14 (2.5) | 0.31 |
Mold | 17 (1.2) | 14 (1.5) | 0.48 | 169 (5.3) | 104 (4.5) | 0.21 | 1418 (13.6) | 939 (13.0) | 0.28 | 1596 (19.8) | 906 (18.7) | 0.12 | 204 (23.1) | 112 (19.6) | 0.12 |
Grass | 9 (0.6) | 5 (0.5) | 0.80 | 22 (0.7) | 20 (0.9) | 0.44 | 140 (1.3) | 69 (1.0) | 0.020 | 146 (1.8) | 60 (1.2) | 0.012 | 22 (2.5) | 13 (2.3) | 0.80 |
Trees | 41 (2.8) | 29 (3.1) | 0.67 | 146 (4.5) | 84 (3.7) | 0.10 | 521 (5.0) | 353 (4.9) | 0.77 | 376 (4.7) | 197 (4.1) | 0.11 | 35 (4.0) | 29 (5.1) | 0.31 |
Mulberry | 7 (0.5) | 3 (0.3) | 0.56 | 35 (1.1) | 12 (0.5) | 0.024 | 139 (1.3) | 63 (0.9) | 0.005 | 110 (1.4) | 54 (1.1) | 0.22 | 13 (1.5) | 11 (1.9) | 0.50 |
Amaranth | 11 (0.8) | 6 (0.6) | 0.75 | 45 (1.4) | 24 (1.0) | 0.24 | 144 (1.4) | 80 (1.1) | 0.12 | 100 (1.2) | 48 (1.0) | 0.19 | 20 (2.3) | 5 (0.9) | 0.047 |
Aeroallergen | 261 (18) | 156 (16.9) | 0.47 | 1069 (33.2) | 650 (28.2) | < 0.001# | 5745 (54.9) | 3630 (50.2) | < 0.001# | 5319 (66.1) | 2911 (60.1) | < 0.001# | 628 (71.0) | 352 (61.8) | < 0.001# |
Milk | 259 (17.9) | 165 (17.8) | 0.98 | 704 (21.9) | 460 (20.0) | 0.09 | 2067 (19.8) | 1270 (17.6) | < 0.001# | 1371 (17.0) | 721 (14.9) | 0.001# | 140 (15.8) | 66 (11.6) | 0.023 |
Beef | 4 (0.3) | 3 (0.3) | 0.83 | 36 (1.1) | 28 (1.2) | 0.74 | 206 (2.0) | 138 (1.9) | 0.78 | 158 (2.0) | 80 (1.7) | 0.20 | 15 (1.7) | 7 (1.2) | 0.48 |
Nut | 99 (6.8) | 58 (6.3) | 0.59 | 394 (12.3) | 260 (11.3) | 0.28 | 1159 (11.1) | 695 (9.6) | 0.002# | 583 (7.2) | 287 (5.9) | 0.004 | 43 (4.9) | 25 (4.4) | 0.67 |
Egg | 288 (19.9) | 186 (20.1) | 0.90 | 716 (22.3) | 453 (19.7) | 0.021 | 2146 (20.5) | 1579 (21.8) | 0.033 | 996 (12.4) | 643 (13.3) | 0.14 | 65 (7.4) | 41 (7.2) | 0.91 |
Crab | 41 (2.8) | 34 (3.7) | 0.25 | 297 (9.2) | 191 (8.3) | 0.23 | 791 (7.6) | 461 (6.4) | 0.003 | 327 (4.1) | 124 (2.6) | < 0.001# | 36 (4.1) | 8 (1.4) | 0.004 |
Shrimp | 29 (2.0) | 28 (3.0) | 0.11 | 216 (6.7) | 132 (5.7) | 0.14 | 601 (5.7) | 348 (4.8) | 0.007 | 268 (3.3) | 101 (2.1) | < 0.001# | 35 (4.0) | 7 (1.2) | 0.002# |
Mango | 18 (1.2) | 4 (0.4) | 0.044 | 23 (0.7) | 13 (0.6) | 0.49 | 94 (0.9) | 57 (0.8) | 0.43 | 51 (0.6) | 18 (0.4) | 0.048 | 6 (0.7) | 4 (0.7) | 0.96 |
Food allergen | 534 (36.9) | 338 (36.5) | 0.87 | 1339 (41.6) | 888 (38.6) | 0.023 | 3930 (37.6) | 2556 (35.4) | 0.003 | 2339 (29.1) | 1291 (26.6) | 0.003 | 229 (25.9) | 114 (20.0) | 0.010 |
Overall allergen | 652 (45) | 410 (44.3) | 0.74 | 1806 (56.2) | 1190 (51.7) | 0.001# | 7036 (67.3) | 4590 (63.5) | < 0.001# | 5790 (71.9) | 3247 (67.0) | < 0.001# | 653 (73.9) | 383 (67.2) | 0.006 |