Table 3 Cox proportional hazard regression comparing mortality and hospitalizations among patients with idiopathic pulmonary fibrosis with and without metformin use
| Â | Â | Rate per 100 (95% CI) | Â | Â | Â | |
|---|---|---|---|---|---|---|
| Â | Before propensity score matching | After propensity score matching | Hazard ratio (95% CI) | p value | ||
|  | No metformin (n = 2222) | Metformin (n = 1377) | No metformin (n = 1100) | Metformin (n = 1100) | ||
Death | 25.1 (23.3, 27.1) | 10.5 (8.7, 12.5) | 20.6 (18.4, 23.2) | 10.5 (8.5, 12.8) | 0.46 (0.36, 0.58) |  < 0.001 |
Hospitalization | 76.1 (72.0, 80.6) | 55.12 (50.4, 60.3) | 64.3 (59.2, 69.9) | 57.8 (52.4, 63.8) | 0.82 (0.72, 0.93) | 0.003 |