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Table 3 Survival analyses for number of comorbidities and Charlson comorbidity index

From: Comorbidities in unclassifiable interstitial lung disease

Parameter

Univariate analysis (95% CI)

Multivariate analysis (95% CI)

1-year survival (95% CI)

3-year survival (95% CI)

Number of comorbidities

0

Ref

Ref

0.91 (0.74–0.97)

0.80 (0.56–0.92)

1–3

1.07 (0.47–2.41)

0.78 (0.34–1.81)

0.90 (0.83–0.94)

0.74 (0.65–0.82)

4 or more

1.40 (0.56–3.50)

0.90 (0.35–2.31)

0.86 (0.71–0.93)

0.64 (0.46–0.78)

 ≤ median (0–2)

Ref

Ref

0.89 (0.83–0.93)

0.79 (0.70–0.86)

 > median (3 or more)

1.46 (0.86–2.49)

1.12 (0.64–1.95)

0.88 (0.78–0.94)

0.63 (0.49–0.74)

Charlson comorbidity index

 ≤ median (0)

Ref

Ref

0.88 (0.79–0.93)

0.77 (0.64–0.85)

 > median (1 or more)

1.17 (0.68–2.03)

0.75 (0.42–1.35)

0.90 (0.83–0.94)

0.71 (0.61–0.79)

  1. Data are presented as hazard ratios or percent survivors with 95% confidence intervals (CI). Hazard ratios > 1 indicate an association with increased mortality. Multivariate analyses are adjusted for gender, age, and FVC% predicted. Ref.: Reference group