Table 1 Treatable traits, measurement instrument and cut-off values used for interpretation in people with chronic obstructive pulmonary disease
Treatable traits | Measurement instrument | Cut-off used for interpretation |
|---|---|---|
Pulmonary traits | ||
Mild airflow obstruction [17] | FEV1%pred [17] | ⩾80%pred [17] |
Moderate airflow obstruction [17] | FEV1%pred [17] | 50⩽FEV1 < 80%pred [17] |
Severe airflow obstruction [17] | FEV1%pred [17] | 30% ⩽FEV1 < 50%pred [17] |
Very severe airflow obstruction [17] | FEV1%pred [17] | < 30%pred [17] |
Frequent exacerbations | Clinical history in the previous year [17] | ≥ 2 exacerbations or ≥ 1 hospitalisation in the previous year [17] |
Extra-pulmonary traits—physical | ||
Poor nutritional status | BMI [54] | BMI < 21 or BMI > 30 kg/m2 [54] |
Lower-limb muscle dysfunction | QMS measured with the HHD [24] | |
Low functional status | 1minSTS [25] | |
Extrapulmonary traits—symptoms and health status | ||
Activity-related dyspnoea | mMRC [21] | |
Impact of the disease | CAT [20] | ≥ 18 points [2] |
Symptoms of anxiety | HADS [22] | ≥ 8 points in HADS-A [22] |
Symptoms of depression | HADS [22] | ≥ 8 points in HADS-D [22] |
Impact on health-related quality of life | SGRQ [23] | ≥ 25 points [17] ≥ 46 points [2] |
Extrapulmonary traits—behavioural/life-style risk factors | ||
Current smoking | Clinical history [17] | Positive at the moment of assessment |
Physical inactivity | Brief physical activity assessment tool (BPAAT) | ≤ 3 points [19] |