Comparison between pressure support ventilation and T-piece in spontaneous breathing trials

Respiratory Research

Table 4 Univariable and multivariable analyses with logistic regression model for probability of successful weaning (N = 787)

	Univariable			Multivariable
	OR	95% CI	p-value	Adjusted OR	95% CI	p-value
SBT with PSV	1.11	0.74–1.68	0.608	0.64	0.32–1.27	0.199
Chronic renal failure	1.78	0.92–3.44	0.088	2.42	0.75–7.81	0.138
Solid/hematologic malignancy	0.63	0.40–0.98	0.039	0.75	0.35–1.59	0.451
Steroid use	0.60	0.40–0.90	0.013	0.47	0.24–0.92	0.027
RASS score^a
RASS < − 1	0.38	0.25–0.58	< 0.001	0.77	0.35–1.67	0.509
RASS > + 1	0.81	0.23–2.82	0.741	0.35	0.06–2.09	0.250
Duration of MV before first SBT, days	0.92	0.88–0.96	< 0.001	0.96	0.89–1.04	0.357
Weak cough capacity	0.34	0.21–0.57	< 0.001	0.51	0.25–1.07	0.074
Tracheostomy	0.33	0.22–0.52	< 0.001	0.38	0.16–0.90	0.027
Peak inspiratory pressure, cmH₂O	0.91	0.86–0.95	< 0.001	0.90	0.81–1.01	0.069
Respiratory rate, breath/min	0.96	0.94–0.99	0.011	1.00	0.95–1.05	0.881
PaCO₂, mmHg	0.98	0.96–1.00	0.077	1.00	0.96–1.04	0.912
PaO₂/FiO₂ ratio	1.00	1.00–1.00	0.033	1.00	1.00–1.00	0.501
SOFA score except respiratory system	0.88	0.83–0.93	< 0.001	0.87	0.78–0.96	0.007

CI confidence interval, FiO₂ fraction of inspired oxygen, MV mechanical ventilation, OR odds ratio, PaCO₂ partial pressure of carbon dioxide in arterial blood, PaO₂ partial pressure of oxygen in arterial blood, PSV pressure support ventilation, RASS Richmond Agitation-Sedation Scale, SBT spontaneous breathing trial, SOFA sequential organ failure assessment
^aThe reference group is a RASS − 1–+ 1

ISSN: 1465-993X