Table 4 sRAGE in different subtypes of emphysema
From: Plasma sRAGE levels strongly associate with centrilobular emphysema assessed by HRCT scans
|  | No Emphysema (LAA below − 950HU < 6%) | Emphysema (LAA below -950HU \(\ge\) 6%) | ||
|---|---|---|---|---|
Homogeneous | Heterogeneous | |||
No dominance − 10% < HD < 10% | Upper HD > 10% | Lower HD <  − 10% | ||
Number | 315 | 125 | 45 | 9 |
Presence COPD | 49%1 | 86%2a | 98% | 100% |
FEV1%pred | 84.7% (20.0)1 | 63.1% (26.5)2a | 56.9% (24.3)3 | 36.6% (10.3) |
%LAA below -950HU | 1.97 (1.65)1 | 13.86 (7.65)2c | 23.38 (9.65) | 29.19 (11.16) |
Centrilobular | 1 (0–4)1 | 3 (0–5) 2c | 4 (3–5)3 | 4 (2–5) |
Paraseptal | 0 (0–2)1 | 0 (0–2)2a | 1 (0–2) | 0 (0–2) |
sRAGE | 2.22 (1.02)1 | 1.89 (0.75)2b | 1.53 (0.73) | 1.57 (0.45) |