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Table 5 Patients with deventilation syndrome under PLBV compared to established NIV

From: Characteristics of the deventilation syndrome in COPD patients treated with non-invasive ventilation: an explorative study

 

Established NIV

PLBV mode

p

Ventilator settings

   

 Inspiratory pressure

17.5 (4.4)

14.6 (3.0)

0.002

 Expiratory pressure

5.8 (1.1)

6.1 (1.3)

0.343

Borg scale

7.2 (1.0)

5.6 (2.0)

0.019

Blood gas analysis

   

 pH

7.419 (0.49)

7.418 (0.37)

0.849

 pCO2(mmHg)

47.2 (5.9)

47.4 (6.3)

0.821

 pO2 (mmHg)

64.6 (12.7)

67.9 (16.4)

0.326

 BE (mmHg)

5.3 (5.5)

5.1 (4.8)

0.696

 \({\text{HCO}}_{3}^{ - }\) (mmHg)

30.5 (6.1)

30.4 (5.4)

0.873

6-min walking test

   

 Distance (m)

114.9 (115.7)

129.8 (132.2)

0.087

Pulmonary function

   

 VCmax (%)

44 (16.0)

48 (16.3)

0.040

 FVC (%)

41 (19.0)

47 (18.4)

0.032

 FEV1 (%)

20 (9.5)

21 (8.2)

0.415

 FEV1/FVC (%)

37 (8.3)

34 (5.4)

0.051

 Inspiratory flow (ml)

59.5 (19.2)

63.5 (15.6)

0.085

  1. Bold values denote statistical significance. n = 10
  2. Measurements immediately after mask removal after a single night in PLBV mode. Data are mean (SD)
  3. pCO2 capillary carbon dioxide pressure, pO2 capillary oxygen pressure, BE base excess, \({\text{HCO}}_{3}^{ - }\) bicarbonate, VCmax maximum vital capacity, FVC forced vital capacity, FEV1: forced expiratory volume in 1 s