Table 1 Baseline demographic data and clinical characteristics
Patients with deventilation syndrome (n = 11) | Patient without deventilation syndrome (n = 20) | p | |
|---|---|---|---|
Baseline data | |||
Sex m/f (%) | 55/45 | 35/65 | |
Age, years | 68.5 (6.5) | 69.9 (6.6) | 0.573 |
BMI (kg/m2) | 22.5 (5.1) | 27.6 (6.5) | |
Ventilator settings | |||
Duration of NIV (months) | 30.7 (38.0) | 21.3 (23.6) | 0.509 |
Inspiratory pressure (mmHg) | 16.7 (4.9) | 16.7 (3.3) | 0.999 |
Expiratory pressure (mmHg) | 5.6 (1.2) | 6.7 (1.4) | 0.051 |
Respiratory rate | 11.78 (3.08), n = 2: none set | 13.67 (1.84), n = 8: none set | |
Ti max (s) | 1.42 (0.24) | 1.21 (0.23) | 0.037 |
Ti min (s) | 0.86 (0.21) | 0.80 (0.24) | 0.461 |
Blood gas analysis | |||
pH | 7.41 (0.02) | 7.40 (0.03) | 0.302 |
pO2 (mmHg) | 63.3 (12.0) | 63.8 (13.2) | 0.914 |
pCO2 (mmHg) | 47.0 (9.7) | 46.7 (7.0) | 0.913 |
Pulmonary function (n = 28) | n = 10 | n = 18 | |
VCmax (l) | 1.56 (0.37) | 1.98 (0.50) | 0.016 |
VCmax (%) | 51 (16.9) | 67 (12.2) | 0.015 |
FVC (%) | 48 (16.3) | 62 (12.8) | |
FEV1 (%) | 29 (14.6) | 38 (11.8) | 0.001 |
FEV1/FVC | 58 (10.2) | 66 (14.2) | 0.148 |
TLC (%) | 136 (20.1) | 124 (31.8) | 0.089 |
RV (%) | 276 (61.8) | 218 (81.5) | 0.060 |
RV/TLC | 78 (5.5) | 69 (7.1) | 0.001 |
Reff (%) | 320 (88.5) | 253 (147) | 0.021 |
SReff (%) | 627 (165.6) | 395 (165.6) | 0.006 |
Rtot (%) | 412 (138.3) | 299 (169.4) | 0.012 |
Inspiratory flow (ml) | 68.2 (16.6) | 72.0 (12.8) | 0.516 |
Exercises | |||
6MWT, distance (m) | 149.9 (112.4) | 236.7 (112.8) | 0.049 |
Muscle strength, time (s) | 60 (48) | 82 (47) | 0.094 |