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Fig. 1 | Respiratory Research

Fig. 1

From: MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model

Fig. 1

MUC5B−/− mice have decreased goblet cell differentiation. MUC5B+/+ mice (n = 15 per group) and MUC5B−/− mice (n = 10 per group). a PAS staining. b MUC5AC IHC. c PAS grade. d MUC5AC IHC score. e ELISA of MUC5AC in BAL fluid. f RT-qPCR of MUC5AC in lung tissue. g ELISA of MUC5B in BAL fluid. h RT-qPCR of MUC5B in lung tissue. “*” indicates a significant difference; ***P < 0.001, **P < 0.01 compared with smoke-exposed MUC5B+/+ mice

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