Table 1 Demographic and clinical characteristics of the study population
Overall population | Surf < 24 h | No-Surf < 24 h | |
|---|---|---|---|
Demographics | |||
N subjects | 61 | 14 | 47 |
Gestational age, median [IQR], weeks | 31.9 [30.3; 32.9] | 31 [30; 32] | 32 [30; 33] |
Birth weight, median [IQR], g | 1490 [1230; 1816] | 1470 [1280; 1780] | 1610 [1230; 1947] |
Small for gestational age, n (%) | 7 (11) | 0 (0) | 7 (15) |
Female, n (%) | 32 (52) | 10 (71) | 22 (47) |
Twins, n (%) | 44 (72) | 9 (64) | 35 (74) |
Cesarian Section, n (%) | 55 (90) | 14 (100) | 41 (87) |
Antenatal steroids, n (%) | 59 (97) | 14 (100) | 45 (96) |
Resuscitation at birth, n (%) | 51 (83) | 14 (100) | 37 (79) |
Apgar score at 5’, median [IQR] | 9 [8; 9] | 9 [8; 9] | 9 [8; 9] |
Arterial cord pH, median [IQR]a | 7.31 [7.27; 7.35] | 7.36 [7.29; 7.36] | 7.30 [ 7.27; 7.33] |
Clinical characteristics | |||
Duration of non-invasive RS, median [IQR], days | 4.1 [1.5; 29.2] | 8.0[5.7; 25.3] | 3.0 [1.0; 29.6]* |
Duration of mechanical ventilation, median [IQR], days | 0.0 [0.0; 0.0] | 0.0 [0.0; 0.4] | 0.0 [0.0; 0.0]* |
Surfactant, n (%) | 17 (32) | 14 (100) | 3 (6)* |
Second surfactant dose, n (%) | 4 (7) | 2 (14) | 2 (4) |
Air-leak, n (%) | 1 (2) | 0 (0) | 1 (2) |
Respiratory support at 36 weeks of gestation, n (%) | 10 (16) | 2 (14) | 8 (17) |
Sepsis, n (%) | 9 (15) | 3 (21) | 6 (13) |
Patent doctus arteriosus, n (%) | 8 (13) | 4 (29) | 4 (8) |
Intraventricular haemorrhage, n (%) | 0 (0) | 0 (0) | 0 (0) |
Necrotizing enterocolites, n (%) | 5 (8) | 2 (14) | 3 (6) |
Hospitalization, median [IQR], days | 34.0 [22.0; 57.7] | 36.0 [29.0; 61.0] | 33.0 [22.0; 54.0] |