Skip to main content

Table 6 Predictors of outcome in the whole follow-up perspective

From: Predictive value of chest HRCT for survival in idiopathic pulmonary arterial hypertension

  DEATH or LTX in in the whole follow-up perspective
Univariate Multivariate
Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value
Male gender 2.11 (1.29–3.45) 0.003   
Cigarette smoking 1.63 (1.01–2.64) 0.045   
WHO FC 3–4 1.92 (1.21–3.06) 0.006   
6MWD [m] 0.9977 ( 0.9957–0.9997) 0.026   
SpO2 [%] 0.91 (0.87–0.96) 0.0003   
6MWT ΔSpO2 1.04 (1.01–1.06) 0.009   
DLCO [%pred] 0.97 (0.96–0.99) 0.0001 0.98 (0.97–0.99) 0.002
NT-proBNP[pg/ml] 1.0002 (1.0001–1.0004) 0.0002   
RAPm [mmHg] 1.07 (1.02–1.12) 0.003   
CO [l/min] 0.77 (0.62–0.97) 0.026   
CI [l/min/m2] 0.59 (0.40–0.89) 0.01   
Svo2 [%] 0.97 (0.95–0.99) 0.013   
Non-responder 3.18 (1.51–6.69) 0.002   
Number of low-risk factors 0.76 (0.66–0.88) 0.0002   
Intermediate/high risk group 4.15 (2.05–8.37) 0.00007 3.84 (1.71–8.59) 0.001
  1. WHO FC, World Health Organisation functional class; 6MWD, 6-min walking test distance; SpO2, blood oxygen saturation; 6MWT ΔSpO2, change of blood oxygen saturation during 6-min walking test; DLCO, diffusion lung capacity for carbon monoxide; NT-proBNP, N-terminal pro-brain natriuretic peptide; RAPm, mean right atrial pressure; CO, cardiac output; CI, cardiac index; SvO2, mixed venous blood oxygen saturation