Table 6 Predictors of outcome in the whole follow-up perspective
From: Predictive value of chest HRCT for survival in idiopathic pulmonary arterial hypertension
DEATH or LTX in in the whole follow-up perspective | ||||
|---|---|---|---|---|
Univariate | Multivariate | |||
Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | |
Male gender | 2.11 (1.29–3.45) | 0.003 | ||
Cigarette smoking | 1.63 (1.01–2.64) | 0.045 | ||
WHO FC 3–4 | 1.92 (1.21–3.06) | 0.006 | ||
6MWD [m] | 0.9977 ( 0.9957–0.9997) | 0.026 | ||
SpO2 [%] | 0.91 (0.87–0.96) | 0.0003 | ||
6MWT ΔSpO2 | 1.04 (1.01–1.06) | 0.009 | ||
DLCO [%pred] | 0.97 (0.96–0.99) | 0.0001 | 0.98 (0.97–0.99) | 0.002 |
NT-proBNP[pg/ml] | 1.0002 (1.0001–1.0004) | 0.0002 | ||
RAPm [mmHg] | 1.07 (1.02–1.12) | 0.003 | ||
CO [l/min] | 0.77 (0.62–0.97) | 0.026 | ||
CI [l/min/m2] | 0.59 (0.40–0.89) | 0.01 | ||
Svo2 [%] | 0.97 (0.95–0.99) | 0.013 | ||
Non-responder | 3.18 (1.51–6.69) | 0.002 | ||
Number of low-risk factors | 0.76 (0.66–0.88) | 0.0002 | ||
Intermediate/high risk group | 4.15 (2.05–8.37) | 0.00007 | 3.84 (1.71–8.59) | 0.001 |