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Fig. 9 | Respiratory Research

Fig. 9

From: Prostaglandin E2 sensitizes the cough reflex centrally via EP3 receptor-dependent activation of NaV 1.8 channels

Fig. 9

Effect of pretreatment with the TRPA1 antagonist, HC-030031, on PGE2-enhanced citric acid-induced cough. Pretreatment of guinea pigs with 15 μl of TRPA1 antagonist, HC-030031 (0.02 mg/ml; n = 7 and 0.05 mg/ml; n = 6, i.c.v.) did not affect the PGE2-enhanced citric acid-induced cough response compared to vehicle (n = 8). Data are plotted as a scatter graph A and a bar chart B showing mean cough ± SEM

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Respiratory Research

ISSN: 1465-993X

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