Table 3 Characteristics of patients with normal and abnormal hypochromic erythrocytes at baseline
From: Prognostic impact of hypochromic erythrocytes in patients with pulmonary arterial hypertension
Hypochromic erythrocytes at baseline | |||
|---|---|---|---|
≤ 2% | > 2% | p-value* | |
n = 41 | n = 21 | ||
Mean ± SD or n (valid %) | Mean ± SD or n (valid %) | ||
Characteristics | |||
Age, years | 62.4 ± 14.3 | 68.1 ± 15.2 | 0.106 |
Height, cm | 166.9 ± 9.8 | 164.9 ± 9.1 | 0.227 |
Weight, kg | 80.5 ± 16.7 | 80.9 ± 21.1 | 0.577 |
Sex, female | 24 (58.5) | 12 (57.1) | 0.916 |
PAH classification | |||
Idiopathic PAH | 19(46.3%) | 3 (14.3%) | 0.036 |
Associated PAH with connective tissue disease | 6 (14.6%) | 6 (28.6%) | |
Portal hypertension | 1 (2.4%) | 0 | |
Associated PAH with congenital heart disease | 0 | 2 (9.5%) | |
Other PAH | 15 (36.6%) | 10 (47.6%) | |
Laboratory | |||
Creatinine, mg/dl | 1.1 ± 0.4 | 1.3 ± 0.5 | 0.054 |
Glomerular filtration rate, % | 72.8 ± 28.1 | 57.4 ± 26.3 | 0.021 |
Iron, µg/dl | 15.0 ± 5.5 | 13.2 ± 6.7 | 0.285 |
Hemoglobin, g/dl | 15.0 ± 1.4 | 14.1 ± 1.8 | 0.048 |
Iron deficiency | 10 (45.5%) | 7 (63.6%) | 0.455 |
Hemoglobin deficiency | 0 | 4 (19%) | 0.004 |
Ferritin < 40, ng/ml | 3 (8.3) | 3 (16.7) | 0.380 |
MCV < 83, fl | 1 (2.4%) | 5 (23.8%) | 0.007 |
MCH < 27, pg/cell | 1 (2.4%) | 3 (14.3%) | 0.072 |
MCHC < 30, g/dl | 0 | 1 (4.8%) | 0.169 |
Diffusion capacity | |||
DLCO SB, % | 55.7 ± 22.2 | 43.4 ± 21.8 | 0.022 |
Echocardiography | |||
Right atrial area, cm2 | 19.8 ± 6.5 | 22.7 ± 6.5 | 0.062 |
Right ventricular area, cm2 | 22.4 ± 5.4 | 24.9 ± 7.8 | 0.211 |
Systolic pulmonary arterial pressure, mmHg | 61.0 ± 20.9 | 59.5 ± 19.7 | 0.855 |
Tricuspid annular plane systolic excursion | 2.1 ± 0.6 | 2.0 ± 0.7 | 0.581 |
Right heart catheter | |||
Right atrial pressure, mmHg | 7.1 ± 4.2 | 9.1 ± 3.9 | 0.053 |
Mean pulmonary arterial pressure, mmHg | 40.2 ± 12.0 | 40.1 ± 9.2 | 0.743 |
Cardiac output, l/min | 4.6 ± 1.2 | 4.6 ± 1.8 | 0.438 |
Pulmonary arterial wedge pressure, mmHg | 9.8 ± 2.8 | 11.3 ± 3.1 | 0.045 |
Pulmonary vascular resistance, dynes*sec*cm−1 | 600.8 ± 363.2 | 590.6 ± 334.3 | 0.970 |