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Fig. 4 | Respiratory Research

Fig. 4

From: Knockdown of circFOXO3 ameliorates cigarette smoke-induced lung injury in mice

Fig. 4

MiR-214-3p overexpression suppressed CS-induced lung inflammatory processes in vivo. A A qRT-PCR analysis of expression levels of CXCL1 and IL-6 mRNAs and miR-214-3p in the lung homogenates of CS-exposed mice treated with either the NC or miR-214-3p agomir. B The inflammatory cytokines CXCL1 and IL-6 in the lung homogenates, according to ELISAs. C Typical images of the H&E-stained lung parenchyma samples. D The separate counts of neutrophils, macrophages, and total cells within mouse BALF. E The infiltration by macrophages was analyzed by CD68 staining in the lungs. F Representative images of immunostaining for CD11b uncovered the infiltration of the lungs by neutrophils; quantitative analysis of the infiltration by CD11b+ cells (as presented on the right). **P < 0.01

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