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Table 1 Top proteins upregulated in IPF plasma compared to healthy controls

From: Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis

Gene Description Log fold change FDR
CCL28 C-C motif chemokine 28 2.259556173 0.000231
CCL25 C-C motif chemokine 25 2.073155182 0.000257
TLR4 Toll-like receptor 4 1.856929692 0.00108
CCL11 Eotaxin 1.799567355 8.20E−05
RSPO3 R-spondin-3 1.729221937 0.004217
UNC5D Netrin receptor UNC5D 1.689658186 0.000147
CCL17 C-C motif chemokine 17 1.621455261 0.000257
TNFSF12 Tumor necrosis factor ligand superfamily member 12 1.578591635 2.52E−06
FRZB Secreted frizzled-related protein 3 1.506003793 0.001032
CCL21 C-C motif chemokine 21 1.40240372 0.000945
CXCL9 C-X-C motif chemokine 9 1.377906373 0.004835
GFRA1 GDNF family receptor alpha-1 1.307361522 0.048836
MDK Midkine 1.272550426 0.035844
PRL Prolactin 1.271289238 8.20E−05
CCL4L1 C-C motif chemokine 4-like 1.25625883 0.054414
MAP2K4 Dual specificity mitogen-activated protein kinase 4 1.218081304 0.006491
PDGFB Platelet-derived growth factor subunit B 1.17880283 0.026191
CCL5 C-C motif chemokine 5 1.145110861 0.010668
AKT2 RAC-beta serine/threonine-protein kinase 1.126278423 0.000147
ICAM5 Intercellular adhesion molecule 5 1.098941547 0.000257
CA6 Carbonic anhydrase 6 1.094703466 0.061433
SPON1 Spondin-1 1.061155009 0.025752
CXCL11 C-X-C motif chemokine 11 1.059045713 0.056945
OLR1 Oxidized low-density lipoprotein receptor 1 1.05710928 0.077666
CTSV Cathepsin L2 1.026447098 0.000346