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Table 2 IPTW-weighted one-year costs after treatment initiation in patients treated with pirfenidone or nintedanib and related cost differences with bootstrapped 95% confidence intervals

From: Pirfenidone vs. nintedanib in patients with idiopathic pulmonary fibrosis: a retrospective cohort study

 

Pirfenidone (N = 840)

Nintedanib (N = 713)

 
 

Costs (in €)

Costs (in €)

Difference (in €)

Overall

Total

33,893 (32,559; 35,251)

34,700 (33,407; 36,636)

− 807 (− 2977; 1220)

 Inpatient

5991 (5247; 7125)

5590 (4739; 7376)

400 (− 1130; 1849)

 Outpatient

1107 (1065; 1160)

1271 (1187; 1410)

− 164 (− 280; − 55)

 Pharmaceuticals

26,796 (25,706; 28,008)

27,839 (26,626; 28,880)

− 1043 (− 2638; 476)

Respiratory-related

Total

29,085 (27,826; 30,344)

30,366 (29,245; 32,082)

− 1282 (− 3423; 534)

 Inpatient

2867 (2369; 3717)

3,096 (2398; 5163)

− 229 (− 1661; 884)

 Outpatient

690 (666; 717)

693 (666; 726)

− 3 (− 42; 37)

 Pharmaceuticals

25,528 (24,416; 26,587)

26,578 (25,443; 27,710)

− 1050 (− 2549; 473)

  1. Statistically significant results are marked in bold
  2. Bootstrapping with 1000 repetitions, bias-corrected and accelerated bootstrap method