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Table 1 Patient characteristics (COSYCONET)

From: IgE is associated with exacerbations and lung function decline in COPD

Parameter (visit 1)

Unit

Median

Interquartile range

Mean

Standard deviation

COSYCONET (n = 2280 patients)

 Age

Years

66.0

59.0–71.0

64.8

8.6

 Years since diagnosis

Years

6.0

3.0–10.0

7.6

6.7

 Weight

kg

77.0

66.0–90.0

79.0

18.0

 Height

Cm

170.0

164.0–177.0

170.5

9.2

 BMI

kg/m2

26.5

23.4–30.1

27.1

5.4

 Pack years

Years

42.0

22.5–64.5

48.4

35.6

 CAT score

Points

18.0

13.0–23.0

18.0

7.3

 mMRC score

Points

1.0

1.0–2.0

1.6

0.9

 6MWT distance

Meters

435.0

360.0–492.8

422.5

107.4

 BODE-Index

Points

2.0

1.0–3.0

2.2

2.0

 SGRQ

Points

56.0

40.2–71.7

55.2

21.4

 No. of Exacerbations

Number

1.0

0–2

1.3

2.8

 FEV1

Liters

1.5

1.1–2.1

1.7

0.7

 FEV1 (% predicted)

%

55.0

41.0–72.0

57.0

21.1

 FEV1%FVC

%

54.8

44.6–65.5

55.2

13.8

 ITGV (% predicted)

%

140.6

117.6–168.2

143.9

37.1

 DLCO (% predicted)

%

53.7

40.0–69.6

55.3

21.6

 Total IgE

IU/ml

46.2

17.3–139.4

176.8

496.1

 Allergen-specific IgE (SX1)

IU/ml

0.11

0.07–0.34

3.04

16.13

  1. BMI, Body mass index; CAT, COPD assessment test; mMRC, Modified Medical Research Council; 6MWT, 6 min walk test; BODE, body-mass index, airflow obstruction, dyspnea, and exercise capacity index; SGRQ, St. George's Respiratory Questionnaire; FEV1, Forced expiratory volume in the first second of expiration; ITGV, intra-thoracic gas volume; DLCO, lung diffusion capacity for carbon monoxide