From: IgE is associated with exacerbations and lung function decline in COPD
Parameter (visit 1) | Unit | Median | Interquartile range | Mean | Standard deviation |
---|---|---|---|---|---|
COSYCONET (n = 2280 patients) | |||||
Age | Years | 66.0 | 59.0–71.0 | 64.8 | 8.6 |
Years since diagnosis | Years | 6.0 | 3.0–10.0 | 7.6 | 6.7 |
Weight | kg | 77.0 | 66.0–90.0 | 79.0 | 18.0 |
Height | Cm | 170.0 | 164.0–177.0 | 170.5 | 9.2 |
BMI | kg/m2 | 26.5 | 23.4–30.1 | 27.1 | 5.4 |
Pack years | Years | 42.0 | 22.5–64.5 | 48.4 | 35.6 |
CAT score | Points | 18.0 | 13.0–23.0 | 18.0 | 7.3 |
mMRC score | Points | 1.0 | 1.0–2.0 | 1.6 | 0.9 |
6MWT distance | Meters | 435.0 | 360.0–492.8 | 422.5 | 107.4 |
BODE-Index | Points | 2.0 | 1.0–3.0 | 2.2 | 2.0 |
SGRQ | Points | 56.0 | 40.2–71.7 | 55.2 | 21.4 |
No. of Exacerbations | Number | 1.0 | 0–2 | 1.3 | 2.8 |
FEV1 | Liters | 1.5 | 1.1–2.1 | 1.7 | 0.7 |
FEV1 (% predicted) | % | 55.0 | 41.0–72.0 | 57.0 | 21.1 |
FEV1%FVC | % | 54.8 | 44.6–65.5 | 55.2 | 13.8 |
ITGV (% predicted) | % | 140.6 | 117.6–168.2 | 143.9 | 37.1 |
DLCO (% predicted) | % | 53.7 | 40.0–69.6 | 55.3 | 21.6 |
Total IgE | IU/ml | 46.2 | 17.3–139.4 | 176.8 | 496.1 |
Allergen-specific IgE (SX1) | IU/ml | 0.11 | 0.07–0.34 | 3.04 | 16.13 |