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Fig. 3 | Respiratory Research

Fig. 3

From: TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathway

Fig. 3

Overexpression of TIPE2 elevated the PDGF-BB-mediated reduction of calponin and SM22α expressions in ASMCs. ASMCs were transfected with pcDNA3.0-TIPE2 or pcDNA3.0 for 48 h and then treated with PDGF-BB. A, B The mRNA expression levels of calponin and SM22α were measured using the qRT-PCR assay. C The protein expression levels of calponin and SM22α were detected using the Western blot assay. D, E Quantification analysis of calponin and SM22α. Control group, *p < 0.05, vs. the pcDNA3.0 + PDGF-BB group, #p < 0.05

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