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Table 5 Literature review for studies evaluating efficacy of prone positioning in mechanically ventilated patients with COVID-19 ARDS

From: Effect of prone positioning on oxygenation and static respiratory system compliance in COVID-19 ARDS vs. non-COVID ARDS

Study author Number of patients Study region Timing of response evaluation Change in PaO2/FiO2 ratio (mmHg) Change in compliance (mL/cmH2O)
Present study by Jimyung Park 23 South Korea End of first proning session Median 107 (IQR 92–132)
→ median 196 (IQR 161–248)
Median 27.2 (IQR 21.9–32.7)
→ median 31.5 (IQR 25.2–37.0)
Osama Abou-Arab [41] 25 France End of first proning session Median 91 (95% CI 78–137)
→ median 124 (95% CI 97–149)
Median 32 (95% CI 21–38)
→ median 32 (95% CI 23–40)
Alfredo J Astua [42] 29 U.S.A End of first proning session Mean 107.5 ± 5.6
→ mean 142.0 ± 10.8
N.A
Max Berrill [43] 34 U.K End of every proning session Mean 99.8 ± 100
→ mean 151.9 ± 58.9
N.A
Jennifer Clarke [44] 20 Ireland During first proning session Median 123 (IQR 100–154)
→ median 286 (IQR 195–348)
Median 33.7 (IQR 30.1–43.0)
→ median 32.5 (IQR 26.7–37.5)
Ivor S Douglas [45] 61 U.S.A 2 h after starting proning Median 99 (IQR 73–128)
→ median 136 (IQR 105–164)
N.A
Helena Gleissman [46] 44 Sweden End of first proning session Median 104 (IQR 86–122)
→ median 161 (IQR 127–207)
N.A
Rohit Khullar [47] 23 U.S.A End of last proning session Mean 84.8 (SD N.A.)
→ mean 202.0 (SD N.A.)
N.A
Thomas Langer [48] 78 Italy End of first proning session Median 98 (IQR 72–121)
→ median 158 (IQR 112–220)
Median 43 (IQR 31–50)
→ median 42 (IQR 35–48)
Mirja Mittermaier [49] 9 Germany 12 h after starting proning Mean 118.4 ± 41.9
→ mean 181.8 ± 63.2
N.A
François Perier [50] 9 France 3 h after starting proning N.A Median 44 (IQR 38–55)
→ median 39 (IQR 32–53)
Ling Sang [51] 20 China End of first proning session Mean 68.0 ± 10.3
→ mean 82.4 ± 15.5
Mean 17.5 ± 3.5
→ mean 20.6 ± 4.4
Gaetano Scaramuzzo [52] 191 Italy 3 h after resupination Median 49% improvement (IQR 19–100%) N.A
Mehdi C Shelhamer [53] 62 U.S.A During first proning session Improvement by 36.4 mmHg (49% improvement) N.A
Richard Vollenberg [54] 13 Germany 6 h after starting proning Median 58% improvement (IQR 31–95%) Median 38 (IQR 26–58)
→ median 39 (IQR 27–59)
Tyler T Weiss [29] 36 U.S.A 2 h after starting proning Median 131 (IQR 87–144)
→ median 208 (IQR 146–268)
Median 29.2 (IQR 23.3–35.5)
→ median 29.2 (IQR 24.0–36.2)
David R Ziehr [55] 122 U.S.A End of first proning session Median 149 (IQR 123–170)
→ median 235 (IQR 186–285)
Median 31 (IQR 27–39)
→ median 33 (IQR 28–38)
  1. CI confidence interval, FiO2 fraction of inspired oxygen, IQR interquartile range, N.A. not available, PaO2 partial pressure of oxygen, SD standard deviation