Table 1 Baseline characteristics of the study subjects
| Â | Cohort for testing procedural safety | Â | Cohort for testing treatment efficacy (at 4Â months after ILAIT) | Â | Cohort for testing treatment efficacy (at 1Â year after ILAIT) | Â | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|  | All subjects(n = 32) | Active group (n = 19) | Control group (n = 13) | P-value | All subjects (n = 30) | Active group (n = 17) | Control group (n = 13) | P-value | All subjects (n = 22) | Active group (n = 13) | Control group (n = 9) | P-value |
Age, year | 34.2 ± 9.5 | 32.4 ± 11.1 | 36.9 ± 5.9 | 0.037 | 34.9 ± 9.3 | 33.4 ± 11.2 | 36.9 ± 5.9 | 0.079 | 36.5 ± 9.7 | 35.2 ± 11.8 | 38.4 ± 5.7 | 0.186 |
No. of Female | 19 (59.4) | 11 (57.9) | 8 (61.5) | 0.565 | 18 (60.0) | 9 (52.9) | 8 (61.5) | 0.410 | 13 (59.1) | 7 (53.8) | 6 (66.7) | 0.439 |
Symptom duration, years | 14.5 ± 9.5 | 15.8 ± 8.7 | 12.8 ± 10.6 | 0.648 | 14.2 ± 9.6 | 15.4 ± 9.0 | 12.8 ± 10.6 | 0.674 | 14.5 ± 10.0 | 13.6 ± 10.3 | 15.4 ± 10.3 | 0.645 |
Comorbid allergic diseases | ||||||||||||
 Asthma | 19 (59.4) | 11 (57.9) | 8 (61.5) | 0.470 | 18 (60.0) | 10 (58.8) | 8 (61.5) | 0.508 | 13 (59.0%) | 7 (53.8) | 6 (66.7) | 0.436 |
 Urticaria | 7 (21.9) | 6 (31.6) | 1 (7.7) | 0.186 | 6 (20.0) | 5 (29.4) | 1 (7.7) | 0.240 | 4 (18.2) | 4 (30.8) | 0 (0.0) | 0.184 |
 Food allergy | 6 (18.8) | 5 (26.3) | 1 (7.7) | 0.294 | 6 (20.0) | 5 (29.4) | 1 (7.7) | 0.240 | 5 (22.7) | 4 (30.8) | 1 (11.1) | 0.423 |
 Drug allergy | 5 (15.6) | 3 (15.8) | 2 (15.4) | 0.660 | 5 (16.6) | 3 (17.7) | 2 (15.4) | 0.657 | 4 (18.1) | 3 (23.1) | 1 (11.1) | 0.652 |
 Atopic dermatitis | 4 (12.5) | 2 (10.5) | 2 (15.4) | 0.542 | 4 (13.3) | 2 (11.8) | 2 (15.4) | 0.591 | 3 (13.6) | 2 (15.4) | 1 (11.1) | 0.642 |
 Family history of allergic diseases | 21 (65.6) | 11 (57.9) | 10 (76.9) | 0.283 | 20 (66.7) | 10 (58.8) | 10 (76.9) | 0.259 | 15 (68.2) | 8 (61.5) | 7 (77.8) | 0.372 |
Target allergen | ||||||||||||
 Dermatophagoides farinae | 22 (68.8) | 13 (68.4) | 9 (69.2) | 0.636 | 20 (66.7) | 11 (64.7) | 9 (69.2) | 0.554 | 15 (68.2) | 8 (61.5) | 7 (77.8) | 0.372 |
 D. pteronyssinus | 21 (65.6) | 13 (68.4) | 8 (61.5) | 0.487 | 19 (63.3) | 11 (64.7) | 8 (61.5) | 0.579 | 14 (63.6) | 8 (61.5) | 6 (66.7) | 0.584 |
 Cat | 19 (59.4) | 10 (52.6) | 9 (69.2) | 0.285 | 18 (60.0) | 9 (52.9) | 9 (69.2) | 0.301 | 12 (54.5) | 7 (53.8) | 5 (55.6) | 0.639 |
 Dog | 8 (25.0) | 5 (26.3) | 3 (23.1) | 0.587 | 7 (23.3) | 4 (23.5) | 3 (23.1) | 0.660 | 6 (27.3) | 3 (23.1) | 3 (33.3) | 0.477 |