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Table 1 Subject characteristics of sputum donors

From: Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis

Clinical data Ex vivo assays
Patient Age span Pack years FEV1 (L) FEV1% of pred FEV1/FVC (%) CATc CB-Qd qPCR TNF qPCR IL1B qPCR CCL3 Steroid resistance
1 70–74 50 2.6 (3.1a) 59 (71a) 53 (59a) 22 34 X X   
2 70–74 7 2.4 79 69 16 31 X X   
3 70–74 44 1.8 57 61 29 38 X X   
4 60–64 47 1.0 (1.1a) 39 (44a) 43 (47a) 31 42 X X X  
5 70–74 75 2.5 88 52 31 39 X X X X
6 60–64 8b 4.3 (4.3a) 97 (98)a 61 (63a) 19 31     X
7 65–69 33 1.7 (2.2a) 44 (56)a 46 (51a) 16 27 X X X X
8 65–69 47 1.5 (1.4a) 60 (57a) 62 (64a) 35 39 X X X X
9 65–69 46 1.4 (1.6a) 56 (63)a 45 (45a) 9 28 X X X X
  1. aSpirometry with bronchodilation
  2. bPipe
  3. cCOPD assessment test
  4. dChronic bronchitis questionnaire