Respiratory Research

Table 1 Subject characteristics of sputum donors

From: Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis

Clinical data								Ex vivo assays
Patient	Age span	Pack years	FEV1 (L)	FEV1% of pred	FEV1/FVC (%)	CAT^c	CB-Q^d	qPCR TNF	qPCR IL1B	qPCR CCL3	Steroid resistance
1	70–74	50	2.6 (3.1^a)	59 (71^a)	53 (59^a)	22	34	X	X
2	70–74	7	2.4	79	69	16	31	X	X
3	70–74	44	1.8	57	61	29	38	X	X
4	60–64	47	1.0 (1.1^a)	39 (44^a)	43 (47^a)	31	42	X	X	X
5	70–74	75	2.5	88	52	31	39	X	X	X	X
6	60–64	8^b	4.3 (4.3^a)	97 (98)^a	61 (63^a)	19	31				X
7	65–69	33	1.7 (2.2^a)	44 (56)^a	46 (51^a)	16	27	X	X	X	X
8	65–69	47	1.5 (1.4^a)	60 (57^a)	62 (64^a)	35	39	X	X	X	X
9	65–69	46	1.4 (1.6^a)	56 (63)^a	45 (45^a)	9	28	X	X	X	X

^aSpirometry with bronchodilation
^bPipe
^cCOPD assessment test
^dChronic bronchitis questionnaire

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ISSN: 1465-993X

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