From: Idiopathic pulmonary fibrosis and diabetes mellitus: a meta-analysis and systematic review
Study characteristic | Study | IPF (D/T) | Control Group (D/T) | OR | 95%CI | P value | Heterogeneity | ||
---|---|---|---|---|---|---|---|---|---|
7 | 698 | 4891 | 2142 | 18,420 | 1.43 | 1.16–1.76 | P = 0.0007 | I2 = 55% | |
4 | 203 | 1581 | 598 | 6138 | 1.52 | 1.05–2.19 | P = 0.02 | I2 = 65% | |
Control groups made up of general population [7, 10, 25,26,27,28] | 6 | 721 | 4795 | 2135 | 18,212 | 1.49 | 1.19–1.88 | P = 0.0007 | I2 = 66% |
2 | 24 | 201 | 23 | 620 | 2.23 | 0.56–8.88 | P = 0.25 | I2 = 79% | |
Healthy control group [24] | 1 | 30 | 100 | 50 | 263 | 1.83 | 1.08–3.09 | … | … |
2 | 47 | 152 | 71 | 447 | 2.50 | 1.24–5.06 | P = 0.01 | I2 = 59% | |
7 | 728 | 4944 | 2137 | 18,648 | 1.47 | 1.17–1.84 | P = 0.008 | I2 = 61% | |
Diagnosis of IPF based on ATS/ERS criteria [7,8,9, 24,25,26] | 6 | 170 | 857 | 402 | 3080 | 2.09 | 1.34–3.29 | P = 0.001 | I2 = 66% |
5 | 193 | 761 | 395 | 2872 | 2.38 | 1.43–3.97 | P = 0.0009 | I2 = 72% | |
2 | 43 | 204 | 57 | 323 | 1.62 | 1.02–2.58 | P = 0.04 | I2 = 0 |