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Fig. 8 | Respiratory Research

Fig. 8

From: RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma

Fig. 8

Lung DEGs from the HDM model ± RORγt inhibitor were compared with sputum DEGs from UBIOPRED that have been segregated according to the Transcriptomic-associated clusters (TACs) defined by Kuo et al. [38]. The left-hand side depicts DEGs in individual animals and the right-hand side depicts an averaged response within the treatment group. A purple color indicates no response, with lighter colors indicating an upregulation and darker colors indicating a downregulation

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Respiratory Research

ISSN: 1465-993X

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