Fig. 4

The long-term effect of postnatal hypoxia on the pulmonary vasculature of adult rats. a A comparison of lung/body wet weight ratio in adult rats who had been exposed to postnatal hypoxia (N = 6 per group). b Right ventricular hypertrophy (Fulton) index [RV / (LV + S)] differed between hypoxia and normoxia rats at 9 weeks old (N = 6–7 per group). c Comparison of mean pulmonary arterial pressure (mPAP) between the groups (N = 5–6 per group). d Immunohistochemical staining of lung tissue and the thickness of pulmonary arterial intima measured by α-SMA (N = 5 per group). e Western blot images of PH-related proteins in the two groups (N = 6 per group). f–i Quantitative analysis of the Western blot experiments (N = 6 per group). *P < 0.05, ** P < 0.01 compared to the control group