Patient-reported dyspnea and health predict waitlist mortality in patients waiting for lung transplantation in Japan

Table 2 Univariable competing risk analysis with the Fine–Gray model in 197 patients waiting for lung transplantation

Characteristics	HR	95% CI	p-value
Sex, male	1.08	0.68–1.71	0.76
Age, years	1.04	1.02–1.06	< 0.001
BMI, kg/m²	1.00	0.94–1.05	0.90
Smoking history	1.01	0.64–1.62	0.96
Charlson comorbidity index	1.01	0.75–1.37	0.96
Interstitial lung disease	2.75	1.70–4.44	< 0.001
Long-term oxygen therapy	0.80	0.43–1.52	0.50
PaO₂, mmHg	1.01	1.00–1.02	0.14
PaCO₂, mmHg	1.02	1.00–1.04	0.041
FVC, L	0.58	0.43–0.80	< 0.001
FVC, %predicted	0.98	0.97–0.99	< 0.001
FEV₁, L	0.92	0.68–1.25	0.61
FEV₁, %predicted	1.00	0.99–1.01	0.89
6-min walk distance, m	1.00	1.00–1.00	0.55
mMRC dyspnea	1.46	1.13–1.87	0.003
SGRQ symptoms	1.02	1.01–1.04	0.0014
SGRQ activities	1.03	1.01–1.05	0.002
SGRQ impacts	1.03	1.02–1.04	< 0.001
SGRQ total	1.04	1.02–1.05	< 0.001
HADS anxiety	1.07	1.02–1.13	0.013
HADS depression	1.05	1.01–1.10	0.024

HR hazard ratio, CI confidence interval, BMI body mass index, PaO₂ arterial partial pressure of oxygen, PaCO₂ arterial partial pressure of carbon dioxide, FVC forced vital capacity, FEV₁ forced expiratory volume in the first second, mMRC modified Medical Research Council, SGRQ St. George’s Respiratory Questionnaire, HADS Hospital Anxiety and Depression Scale

ISSN: 1465-993X