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Table 1 Baseline characteristics of the sample

From: Trends in oral corticosteroids use in severe asthma: a 14-year population-based study

Variable

Value

Total sample

21,144

Female; N (%)

11,722 (55.4%)

Age at index date; Mean (SD)

28.7 (9.4)

Socio-economic status; N (%)

 Quintile 1

4624 (21.9%)

 Quintile 2

4030 (19.1%)

 Quintile 3

4077 (19.3%)

 Quintile 4

4073 (19.2%)

 Quintile 5

3916 (18.5%)

 Unknown

424 (2%)

Variables estimated during follow-up

 Patient years with severe asthma

40,803

 Patient years associated with maintenance OCS use

3348 (8.2%)

 Episodic OCS use; mean number of episodes (SD)

0.89 (0.79)

 Patient-years with at least one episodic use of OCS; N (%)

30,684 (75%)

 Patient-years with asthma-related hospital admission; N (%)

1502 (3.7%)

 Patient-years with asthma-related physician visits; N (%)

 GP visits

25,425 (62.3%)

 Respirologist

1983 (4.9%)

 General internist

1012 (2.5%)

 SABA canisters used per patient-year, Mean (SD)

6.2 (5.4)

 Medication Possession Ratio for ICS per patient-year; mean (SD)

26.7% (29.4%)

Comorbidity: N(%)

 Group 1 (Myocardial infarction)

90 (0.2%)

 Group 2 (Congestive heart failure)

369 (0.9%)

 Group 3 (Peripheral vascular disease)

169 (0.4%)

 Group 4 (Cerebrovascular disease)

173 (0.4%)

 Group 5 (Dementia)

84 (0.2%)

 Group 6 (Chronic pulmonary disease)

7818 (19.2%)

 Group 7 (Connective tissue disease)

641 (1.6%)

 Group 8 (Peptic ulcer disease)

308 (0.8%)

 Group 9 (Mild liver disease)

581 (1.4%)

 Group 10 (Diabetes without complication)

2105 (5.2%)

 Group 11 (Diabetes with complication)

130 (0.3%)

 Group 12 (Paraplegia and Hemiplegia)

81 (0.2%)

 Group 13 (Renal disease)

276 (0.7%)

 Group 14 (Cancer)

435 (1.1%)

 Group 15 (Moderate or Severe liver Disease)

67 (0.2%)

 Group 16 (Metastatic Carcinoma)

78 (0.2%)

 Group 17 (AIDS/HIV)

162 (0.4%)

  1. OCS oral corticosteroid, ICS inhaled corticosteroids, SABA short-acting beta agonists, SD standard deviation