Fig. 1
From: Analysis of single nucleotide polymorphisms in chronic beryllium disease
Sarcoidosis and chronic beryllium disease (CBD) share granuloma formation and clinical phenotype as common hallmarks. Genetic studies propose specific SNPs (e.g. in the BTNL2 and ANXA11 genes) contributing to disease development. Red—indicating enhanced susceptibility and green + indicating protection in sarcoidosis. In CBD, these SNPs influence disease initiation and progression differentially, which has not been studied so far in sarcoidosis. (APC: antigen presenting cells)