Table 3 Logistic regression analysis of the in-hospital mortality of AECOPD requiring RICU admission
From: Predictors of mortality in COPD exacerbation cases presenting to the respiratory intensive care unit
Variable | Univariable OR (95%CI) | P value | Multivariable OR (95%CI) | P value |
|---|---|---|---|---|
Age, years | 1.03 (0.99–1.07) | 0.185 | ||
Gender (M/F) | 1.77 (0.79–3.95) | 0.163 | ||
Requirement for IMV | 25.46 (12.04–53.83) | < 0.001 | 30.31 ( 8.29–110.74) | < 0.001 |
The admission index of ADL | 0.98 (0.97–1.00) | 0.004 | 0.99 (0.97 -1.02) | 0.578 |
Smoking status (ever vs. never) | 1.33 (0.59–2.98) | 0.491 | ||
CHF | 5.30 (2.74–10.23) | 0.001 | 7.63 (2.27–25.64) | 0.001 |
White blood cell count, × 109/L | ||||
< 4 | 3.95 (1.31–11.94) | 0.015 | 5.77 (1.05–31.74) | 0.044 |
4–10 | 1.00 (ref) | 1.00 (ref) | ||
> 10 | 2.81 (1.42–5.54) | 0.003 | 3.05 (0.90–10.31) | 0.073 |
Lymphocyte count, × 109/L | ||||
< 0.8 | 3.85 (1.98–7.47) | < 0.001 | 3.60 (1.10–11.76) | 0.034 |
≥ 0.8 | 1.00 (ref) | 1.00 (ref) | ||
Platelet count, × 109/L | ||||
< 100 | 2.56 (1.23–5.82) | 0.025 | 1.64 (0.30–8.91) | 0.652 |
≥ 100 | 1.00 (ref) | 1.00 (ref) | ||
NLR, % | 1.02 (1.01–1.04) | 0.008 | 1.01 (0.99–1.03) | 0.292 |
PLR, % | 1.00 (1.00–1.00) | 0.115 | ||
CRP, mg /L | ||||
< 10 | 1.00 (ref) | 1.00 (ref) | ||
≥ 10 | 2.55 (1.21–5.45) | 0.016 | 5.57 (0.99–31.30) | 0.051 |
Albumin, g/L | ||||
< 35 | 1.93 (1.00–3.70) | 0.049 | 1.81 (0.51–6.40) | 0.356 |
≥ 35 | 1.00 (ref) | 1.00 (ref) | ||
NT-pro BNP, pg/L | 1.00 (1.00–1.00) | 0.014 | 1.00 (1.00–1.00) | 0.163 |
D-dimer, ug/L | ||||
< 500 | 1.00 (ref) | 1.00 (ref) | ||
500–1000 | 2.08 (0.98–4.42) | 0.057 | 1.07 (0.26–4.33) | 0.931 |
> 1000 | 2.97 (1.33–6.63) | 0.008 | 1.97 (0.44–8.65) | 0.369 |
PaCO2, mmHg | 0.97 (0.95–1.00) | 0.026 | 0.99 (0.94–1.05) | 0.508 |