Asthma-related inflammation promotes lung metastasis of breast cancer cells through CCL11–CCR3 pathway

Table 1 Differential cell counts (percentages) in the bronchoalveolar lavage fluid after treatment with PBS or OVA inhalation and subcutaneous injection of 4T1 cells

Differential cell counts
n = 8	INH		INH + 4T1 subcutaneous injection
Cell type	PBS	OVA	PBS	OVA
Eosinophils	3.53 ± 0.39	29.5 ± 5.74	11 ± 1.86	17.3 ± 5.15
Neutrophils	6.1 ± 1.43	5.46 ± 1.39	27.35 ± 1.74	46.31 ± 5.16**
Lymphocytes	0.10 ± 0.10	0.0 ± 0.0	0.0 ± 0.0	0.77 ± 0.43
Epithelial cells	5.83 ± 1.93	5.13 ± 1.72	1.62 ± 0.69	2.81 ± 0.97
Macrophages	84.3 ± 2.8	59.7 ± 4.3*	59.9 ± 2.76	32.63 ± 6.6**

Proteins level expression of CCL11
n = 8	INH		INH + 4T1 subcutaneous injection
CCL11 (pg/ml)	PBS	OVA	PBS	OVA
Mean ± SEM	0,21 ± 0,04	0,58 ± 0,12*	0,36 ± 0,07	0,42 ± 0,08

Proteins level expression of CCL11 (pg/ml) in lung of mice exposed to PBS or OVA and subcutaneously injected with 4T1 cells. *p < 0.05, **p < 0.01.

ISSN: 1465-993X