Table 1 Demographic characteristics of asthmatics according to the presence of IgG and IgA against Chlamydia pnaumoniae

N

145 (35.5%)

193 (47.5%)

68 (17%)

Gender (F, %)

68

63

49*^##

Age (years)

47 ± 16

51 ± 17*

57.5 ± 13***^#

Age of onset (years)

34 ± 22

35 ± 22

39 ± 22

Asthma duration (years)

8 (1–23)

10 (3–26)

14.5 (2.5–25)*

BMI (Kg/m2)

26.5 (22.6–29.4)

27 (23.4–30.9)

26.4 (23.3–30)

Tobacco

Smokers (%, PY)

12.4 (13 (0.3–60)

18.1 (21 (1.4–58)

19.1 (25 (4–68)

Ex-smokers (%, PY)

27.6 (9 (0.2–75)

25.9 (16 (0.8–83)

35.3 (22 (0.8–75)

Non-smokers (%)

60

56

46 *

Environment

City (%)

24

23

27

Country side (%)

38

44

47

Suburban (%)

30

26

22

Atopy (Y, %)

50

50

49

Exacerbations (n)

0.88 ± 1.70

0.86 ± 1.60

1.06 ± 2.04

Classification

Mild (%)

56

55

38*^#

Moderate (%)

16

19

29*

Severe (%)

28

26

31

Dose of ICS (equivalent of beclomethasone)

760 ± 825

795 ± 1034

1022 ± 1042*

Oral corticoids (Y, %)

10

11

10

Biologics (Y, %)

5

3

0

Anti-IgE (n)

1

2

0

Anti-IL5 (n)

4

2

0

Long-term macrolides (Y, %)

2

0.5

3

Antileukotrienes (Y, %)

23

29

29

ACT

15.5 ± 5.2

15.5 ± 5.6

14.5 ± 0.7

ACQ

1.88 ± 1.16

1.99 ± 1.30

2.19 ± 1.13

AQLQ

4.61 ± 1.41

4.52 ± 1.48

4.29 ± 1.28