Table 6 The characteristics of clusters in SIPFR
Variables | Cluster | P-value | ||
|---|---|---|---|---|
1 (n:55) | 2 (n:79) | 3 (n:39) | ||
A | ||||
Age, years, at enrolment | 73 (72–80) | 73 (65–77) | 68 (66–72) | < 0.001 |
BMI, kg·m2 | 26.9 (25.0–28.6) | 25.8 (23.6–30.8) | 27.7 (24.8–30.6) | 0.575 |
Male (yes, %) | 48 (87.3) | 33 (47.1) | 27 (69.2) | < 0.001 |
Smoking history, (yes, %) | 44 (80) | 53 (75.7) | 26 (66.7) | 0.333 |
6MWD, m | 397 (296–464) | 354 (398–516) | 415 (377–474) | 0.002 |
LpSaO2, % | 87 (82–90) | 90 (87–93) | 84 (81–90) | < 0.001 |
Comorbidities | ||||
The number of comorbidities | 3 (2–3) | 1 (0–2) | 1 (1–1) | < 0.001 |
CCI | 6 (5–7) | 4 (3–5) | 4 (3–4) | < 0.001 |
Acid reflux, (yes, %) | 24 (43.6) | 21 (30) | 13 (33.3) | 0.273 |
Heart diseases, (yes, %) | 53 (96.4) | 29 (41.4) | 15 (38.5) | < 0.001 |
Severity | ||||
FVC% predicted ≥ 75%, (n, %) | 23 (41.8) | 56 (80) | 2 (5.1) | < 0.001 |
DLCO predicted ≥ 55%, (n, %) | 9 (16.4) | 46 (65.7) | 6 (15.4) | < 0.001 |
TLC predicted ≥ 65%, (n, %) | 19 (34) | 62 (88.6) | 12 (30.8) | < 0.001 |
CPI ≤ 45%, (n, %) | 12 (21.8) | 62 (88.6) | 2 (5.1) | < 0.001 |
GAP stage 1, (n, %) | 3 (5.5) | 66 (94.3) | 6 (15.4) | < 0.001 |