Fig. 1
From: LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway
SNHG16 was highly expressed in BLM-induced pulmonary fibrotic tissues. a BLM-induced pulmonary fibrotic tissues were checked by HE-staining (7 days, 14 days and 28 days after BLM injection). b The expression of α-SMA was detected by IHC (0 day, 7 days, 14 days and 28 days after BLM injection). c The expression level of E-cadherin, collagen 1 and fibronectin 1 in pulmonary fibrotic tissues were determined by western blot (7 days, 14 days and 28 days after BLM injection). d The expression level of SNHG16 was determined by qRT-PCR (7 days, 14 days and 28 days after BLM injection). Data were expressed as mean ± SD. Six mice were used in each group (n = 6) **P < 0.01 vs baseline, $$P < 0.01 vs 7 days saline; ##P < 0.01 vs 7 days BLM; &&P < 0.01 vs 14 days saline; @@P < 0.01 vs 28 days saline, represent statistically difference