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Table 4 Principal component analysis (PCA), using a rotated solution (Varimax), with the diffuse alveolar damage and vascular parameters

From: Tracking the time course of pathological patterns of lung injury in severe COVID-19

  Principal component analysis
1 2 3
Normal lung − 0.925 − 0.054 0.206
Exudative DAD 0.078 − 0.743 − 0.449
Intermediate DAD 0.732 0.028 0.384
Advanced DAD 0.107 0.882 − 0.186
Arterial thrombosis − 0.087 0.119 0.713
Capillary thrombosis 0.368 − 0.146 0.585
  1. Factor 1 was related to normal lung and intermediate DAD, factor 2 was associated with the exudative and advanced DAD, and factor 3 was related to arterial thrombosis, showing that vascular changes clustered apart from DAD patterns
  2. DAD diffuse alveolar damage. Variables with a factor loading score of 0.7 were used to assist in the interpretation of rotated factors followed by PCA
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