Table 5 Univariate and multivariate analysis of the effects of ICS cessation compared to continuing triple therapy on secondary outcomes in the outcome year

Exacerbation rate

Managed in primary care

1.05

0.95 to 1.17

0.330

1.33

1.10 to 1.60

0.003

Resulting in A&E attendance

1.24

0.95 to 1.62

0.109

1.72

1.03 to 2.86

0.036

Change in FEV1

− 30.03

− 61.39 to 1.33

0.061

− 24.85

− 55.55 to 5.84

0.112

CAT score

 ≥ 10

0.97

0.67 to 1.43

0.884

1.02

0.60 to 1.76

0.936

mMRC dyspnea score

 ≥ 2

0.88

0.74 to 1.04

0.129

0.77

0.54 to 1.10

0.161