Skip to main content

Table 5 Required number of primary endpoint events

From: Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy – the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial

 

HR = 0.50

HR = 0.55

HR = 0.60

HR = 0.65

HR = 0.70

HR = 0.75

80% power

65

88

120

169

247

379

85% power

75

100

138

194

282

434

90% power

87

118

161

226

330

508

  1. Calculations performed using nQuery 7.0 and assume a 0.05 type I error rate (two-sided) with 1:1 randomization
Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us