Adaptive NKG2C+ natural killer cells are related to exacerbations and nutritional abnormalities in COPD patients

Respiratory Research

Table 1 Main general and functional data of the overall population of COPD patients

COPD patients	n	\( \overline{\mathrm{X}} \)±SD
Age (years)	66	70 ± 8
Sex (male %)	66	52(82)
Tobacco (pack-year)	66	41 ± 11
Anthropometry
Weight (kg)	66	71 ± 18
BMI (kg/m²)	66	26.2 ± 6.5
FFMI (kg/m²)	52	16.9 ± 2.7
Exacerbations (n)	66	1.3 ± 1.2
Blood test and flow cytometry
Eosinophils (total/mm³)	66	199 ± 164
HCMV+ (%)	35	31(89)
NK	59	19.1 ± 10
NKG2C+	63	14.4 ± 17
NKG2A+	46	29.2 ± 17
Functional testing
FEV₁ (% pred.) pre/post bd	66	37 ± 14/39 ± 15
FEV₁/FVC (%) pre/post bd	66	44 ± 11/44 ± 12
RV/TLC (%)	60	63 ± 11
DLco (% pred.)	60	44 ± 20
Kco (% pred.)	60	51 ± 20
SpO₂ (%)	66	93 ± 3
6MWT (m)	56	359 ± 122
CT Scan
Emphysema (%)	58	44(76)
Bronchiectasis (%)	58	13(22)

Data are presented as means ± standard deviation (\( \overline{\mathrm{X}} \) ±SD) or n(percentages). Abbreviations: BMI body mass index; FFMI fat free mass index; FEV₁ forced expiratory volume in the first second; bd bronchodilator; FVC forced vital capacity; RV residual volume; TLC total lung capacity; DLco carbon monoxide transfer coefficient; Kco Krogh index (DLco/alveolar volume; SpO₂ oxygen saturation (pulse oximetry); 6MWT six-minute walking test distance. CT computed tomography,

ISSN: 1465-993X