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Fig. 3 | Respiratory Research

Fig. 3

From: Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation

Fig. 3

Protective effect of Curdione on pulmonary fibrosis. a H&E staining analysis for the severity of lung injury in mice after BLM induction. b, c Masson and Sirius red staining analysis for the severity of lung fibrosis in mice following BLM induction. Images were taken under original magnification × 40 (Up) and × 100(Down). d A bar graph showing the semiquantitative ashcroft scores for the severity of fibrosis. e Body weight change during the course of BLM-induced fibrosis. f The rates of hydroxyproline and lung wet weight of all mice studied. Twelve mice were included in each study group. Experimental results were expressed as mean ± standard deviation. The data were analysed by one-way ANOVA. *P < 0.05; **P < 0.01

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