Table 2 Baseline characteristics of patients included in the INPULSIS® pooled data set, by category of decline in FVC % predicted (analysis 1)
≤ 5% decline in FVC (n = 502) | > 5 to ≤ 10% decline in FVC (n = 201) | > 10% decline in FVC (n = 161) | |
|---|---|---|---|
Women, n (%) | 104 (20.7) | 33 (16.4) | 45 (28.0) |
Age, years | 66.9 (8.2) | 65.4 (7.5) | 66.4 (7.7) |
Time since IPF diagnosis, years | 1.7 (1.4) | 1.6 (1.3) | 1.5 (1.2) |
Ethnicity, n (%) | |||
White | 287 (57.2) | 119 (59.2) | 90 (55.9) |
Black | 2 (0.4) | 0 (0) | 0 (0) |
Asian | 149 (29.7) | 56 (27.9) | 50 (31.1) |
Missing | 64 (12.7) | 26 (12.9) | 21 (13.0) |
BMI, kg/m2 | 28.3 (4.4) | 28.1 (4.1) | 27.0 (4.9) |
Smoking history, n (%) | |||
Non-smoker | 128 (25.5) | 64 (31.8) | 50 (31.1) |
Ex-smoker | 345 (68.7) | 132 (65.7) | 108 (67.1) |
Current smoker | 29 (5.8) | 5 (2.5) | 3 (1.9) |
Comorbidities, n (%) | |||
PH | 17 (3.4) | 6 (3.0) | 3 (1.9) |
COPD | 15 (3.0) | 4 (2.0) | 2 (1.2) |
Lung cancera | 3 (0.6) | 1 (0.5) | 0 (0) |
GERD | 122 (24.3) | 43 (21.4) | 42 (26.1) |
CAD | 48 (9.6) | 9 (4.5) | 12 (7.5) |
FVC, % predicted | 79.2 (17.3) | 82.0 (18.1) | 81.2 (18.0) |
FEV1/FVC ratio | 81.3 (5.6) | 81.2 (5.8) | 82.4 (6.7) |
DLCO, % predicted | 48.1 (13.1) | 48.5 (12.4) | 46.8 (13.1) |